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[生长激素分泌与糖尿病视网膜病变]

[Secretion of GH and diabetic retinopathy].

作者信息

Greco A V, Ricci B, Ghirlanda G, Fedeli G, Altomonte L, Rebuzzi A

出版信息

Minerva Med. 1976 Sep 29;67(45):2902-18.

PMID:967359
Abstract

Recently it has been studied a possible pathogenetic role of GH in diabetic angiopathy. The purpose of the present study was to verify whether the diabetic retinopathy is associated or not with a high plasma GH level. In an attempt to answer this question we did the dosage of plasma GH after a oral glucose load (110 g), Insulin (0,1 U/Kg) i.v., and arginin i.v. (25 g/30'). The plasma GH measurements were approximately the same as in normal patients. The Authors underline the importance of GH in pathophysiology of diabetic angiopathy and report all recent literature on this argument.

摘要

最近,人们研究了生长激素(GH)在糖尿病血管病变中可能的致病作用。本研究的目的是验证糖尿病视网膜病变是否与高血浆生长激素水平相关。为了回答这个问题,我们在口服葡萄糖负荷(110克)、静脉注射胰岛素(0.1单位/千克)和静脉注射精氨酸(25克/30分钟)后测定了血浆生长激素水平。血浆生长激素的测量结果与正常患者大致相同。作者强调了生长激素在糖尿病血管病变病理生理学中的重要性,并报告了关于这一论点的所有最新文献。

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