Castro P F, Bourge R C, McGiffin D C, Benza R L, Fan P, Pinkard N B, McGoon M D
Department of Medicine, The University of Alabama at Birmingham, 35294, USA.
Chest. 1998 Jul;114(1):334-6. doi: 10.1378/chest.114.1.334.
Continuous intravenous infusion of epoprostenol sodium in selected patients with primary pulmonary hypertension improves symptoms and survival. This report describes two patients with primary pulmonary hypertension treated with epoprostenol in whom intrapulmonary shunting and severe hypoxemia occurred. Intrapulmonary shunting was confirmed by contrast echocardiography showing delayed appearance of bubbles in the left cardiac chambers after peripheral venous injection of agitated saline solution.
对部分原发性肺动脉高压患者持续静脉输注依前列醇钠可改善症状并提高生存率。本报告描述了两名接受依前列醇治疗的原发性肺动脉高压患者，他们出现了肺内分流和严重低氧血症。通过对比超声心动图证实存在肺内分流，即在经外周静脉注射搅动生理盐水后，左心室内气泡出现延迟。
