Stippich C, Freitag P, Kassubek J, Sörös P, Kamada K, Kober H, Scheffler K, Hopfengärtner R, Bilecen D, Radü E W, Vieth J B
Abteilung für experimentelle Neuropsychiatrie, Universität Erlangen-Nürnberg, Erlangen, Germany.
Neuroreport. 1998 Jun 22;9(9):1953-7. doi: 10.1097/00001756-199806220-00007.
Functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) were performed in six subjects during self-paced finger movement performance, tactile somatosensory stimulation and binaural auditory stimulation using identical stimulation paradigms. Both functional imaging modalities localized brain activity in adjacent areas of anatomically correct cortex. The mean distances measured between fMRI activity and the corresponding MEG dipoles were 10.1 mm (motor), 10.7 mm (somatosensory), 13.5 mm (auditory right hemisphere) and 14.3 mm (auditory left hemisphere). The distances found may reflect the correlation between electrophysiological and hemodynamic responses due to the different underlying substrates of neurophysiology measured by fMRI and MEG: BOLD contrast vs neuronal biomagnetic activity.
在六名受试者进行自主节奏手指运动、触觉体感刺激和双耳听觉刺激时，使用相同的刺激范式进行了功能磁共振成像（fMRI）和脑磁图（MEG）检查。两种功能成像方式均将大脑活动定位在解剖学上正确的皮质相邻区域。fMRI活动与相应MEG偶极子之间测得的平均距离分别为10.1毫米（运动）、10.7毫米（体感）、13.5毫米（右半球听觉）和14.3毫米（左半球听觉）。所发现的距离可能反映了由于fMRI和MEG测量的神经生理学基础不同而导致的电生理反应与血液动力学反应之间的相关性：血氧水平依赖（BOLD）对比与神经元生物磁活动。
