Dunne E F, Burman W J, Wilson M L
Department of Public Health, Denver Health and Hospitals, Colorado, USA.
Clin Infect Dis. 1998 Jul;27(1):93-6. doi: 10.1086/514612.
Streptomyces species are most widely known for their production of antimicrobial substances and, apart from mycetoma, have rarely been reported as a cause of infection. We describe a patient with early human immunodeficiency virus infection who presented with fever, cough, and nodular pulmonary infiltrates. Open lung biopsy revealed necrotic tissue and a sulfur granule; aerobic bacterial cultures yielded Streptomyces species. The patient was treated successfully with clarithromycin for 6 months. We review the clinical presentation and treatment of invasive streptomyces infections.
链霉菌属因产生抗菌物质而最为人所知，除了足菌肿外，很少被报道为感染的病因。我们描述了一名早期人类免疫缺陷病毒感染患者，该患者出现发热、咳嗽和结节性肺部浸润。开放性肺活检显示坏死组织和硫磺颗粒；需氧菌培养分离出链霉菌属。患者接受克拉霉素治疗6个月后成功治愈。我们回顾了侵袭性链霉菌感染的临床表现和治疗方法。
