Perrin A, Loire R
Arch Mal Coeur Vaiss. 1978 Apr;71(4):387-90.
Sclerodermic cardiomyopathy is the commonest cardiac lesion in this collagen disorder. The picture is a common-place one of left ventricular failure with moderate cardiomegaly (unless there is an associated chronic pericardial effusion). There are no characteristic features on the ECG. The prognosis is particularly poor, with death within one or two years. Clinical presentation of the cardiomyopathy may be preceded by isolated ECG changes occuring over one or two years. The myocardial disorder, which is often associated with latent pericardial and endocardial lesions, is peculiar to scleroderma out of all the collagen disorders, but presents no difficulty in differential diagnosis because of the other features of the disease of which it is a part.
硬皮病性心肌病是这种胶原病中最常见的心脏病变。其表现通常是左心室衰竭伴中度心脏扩大(除非伴有慢性心包积液)。心电图无特征性表现。预后特别差,一两年内死亡。心肌病的临床表现可能在一两年内先出现孤立的心电图改变。这种心肌病变常与潜在的心包和心内膜病变相关,在所有胶原病中硬皮病所特有的,但由于它是该病的一部分,有其他特征,所以在鉴别诊断上没有困难。