Barrillon A, Batiste M, Grand A, Gay J, Gerbaux A
Arch Mal Coeur Vaiss. 1978 Apr;71(4):406-13.
Over the course of 17 years, 7 women have had heart disease either during the last three months of pregnancy or during the first three months post-partum, which appear to be associated with their pregnancy. Enquiries made throughout the country and relating to the last decade have yielded 11 additional cases so far unpublished. The clinical features of these cases do not differ from those of other non-obstructive cardiomyopathies occurring other than in pregnancy. The prognosis depends essentially on the factor of cardiac volume during the first few months of the disorder: if significant cardiomegaly persists, death will follow in one case out of two. There exists the problem of the criteria for making a diagnosis of myocardial disease of pregnancy. It should be emphasised that only 4 of the 18 cases were different from the usual cases of myocardial disease, in that they progressed to recovery which is unusual in this condition. One case was particularly illustrative of this, as clinical cure was followed by a relapse at subsequent pregnancy. Because the pregnancy itself seems to be the cause in such a tiny number of cases, a new hypothesis seems right; this is that pregnancy does no more than aggravate an associated or already existent myocardial disorder.
在17年的时间里,有7名女性在妊娠的最后三个月或产后的前三个月患了心脏病,这些心脏病似乎与她们的妊娠有关。在全国范围内进行的、涉及过去十年的调查到目前为止又发现了11例尚未发表的病例。这些病例的临床特征与妊娠以外发生的其他非梗阻性心肌病并无不同。预后主要取决于疾病最初几个月中心脏容量的因素:如果显著的心脏肿大持续存在,两例中就会有一例死亡。存在着妊娠心肌疾病的诊断标准问题。应该强调的是,18例病例中只有4例与心肌疾病的常见病例不同,因为它们病情好转并康复了,而在这种情况下病情好转并不常见。有一个病例特别能说明这一点,因为临床治愈后在随后的妊娠中又复发了。由于在如此少量的病例中妊娠本身似乎就是病因,所以一个新的假设似乎是正确的;即妊娠只不过是加重了相关的或已经存在的心肌疾病。