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双侧同步性混合性生殖细胞睾丸肿瘤

[Bilaterally synchronous mixed germ cell testicular tumor].

作者信息

Cuervo Pinna C, Rodríguez Rincón J P, Abengozar García-Moreno A, Cabello Padial J, Murillo Mirat J, Sevilla Zabaleta M, Fernández de Alarcón L

机构信息

Servicio de Urología, Hospital Regional Infanta Cristina, Badajoz, España.

出版信息

Arch Esp Urol. 1998 Jun;51(5):477-9.

PMID:9675945
Abstract

OBJECTIVE

To report an uncommon case of bilateral synchronous mixed testicular germ cell tumor.

METHODS

A young male had consulted at our urological services for a unilateral enlarged testis. A testicular tumor was suspected; scrotal US was performed, testicular tumor markers were determined and complementary studies to determine tumor extension were performed.

RESULTS

The US findings suggested a chronic inflammatory condition with bilateral diffuse infiltration, tuberculosis was discarded and bilateral testicular tumor was suspected, which was confirmed by bilateral intraoperative biopsy. A bilateral radical orchidectomy was performed. Adjuvant chemotherapy with cisplatin, VP-16 and bleomycin was administered after bilateral radical orchidectomy due to the attending risk factors for tumor recurrence. The patient is disease-free one year postoperatively.

CONCLUSIONS

Bilateral synchronous testicular germ cell tumors are rare. Scrotal US is a simple, noninvasive and efficient diagnostic imaging method; however, it does not provide pathognomonic images that could indicate the histological nature of the tumor.

摘要

目的

报告一例罕见的双侧同步性混合性睾丸生殖细胞肿瘤病例。

方法

一名年轻男性因单侧睾丸肿大前来我院泌尿外科就诊。怀疑患有睾丸肿瘤;进行了阴囊超声检查,测定了睾丸肿瘤标志物,并进行了其他补充检查以确定肿瘤的扩散情况。

结果

超声检查结果提示为双侧弥漫性浸润的慢性炎症状态,排除了结核病,怀疑为双侧睾丸肿瘤,术中双侧活检证实了这一诊断。实施了双侧根治性睾丸切除术。由于存在肿瘤复发的相关危险因素,双侧根治性睾丸切除术后给予顺铂、依托泊苷和博来霉素辅助化疗。患者术后一年无疾病复发。

结论

双侧同步性睾丸生殖细胞肿瘤较为罕见。阴囊超声是一种简单、无创且有效的诊断成像方法;然而,它无法提供能够表明肿瘤组织学性质的特征性图像。

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