在澳大利亚和委内瑞拉的巨型海蟾蜍（Bufo marinus）体内发现了针对“蛙病毒”的抗体。

Giant toads Bufo marinus in Australia and Venezuela have antibodies against 'ranaviruses'.

作者信息

Zupanovic Z, Lopez G, Hyatt A D, Green B, Bartran G, Parkes H, Whittington R J, Speare R

机构信息

CSIRO, Division of Animal Health, Australian Animal Health Laboratory, Victoria, Australia.

出版信息

Dis Aquat Organ. 1998 Feb 26;32(1):1-8. doi: 10.3354/dao032001.

DOI:10.3354/dao032001

PMID:9676257

Abstract

A serological survey was conducted for antibodies against 'ranaviruses' in the giant toad Bufo marinus in Australia and Venezuela. Sera containing antibodies against 'ranaviruses' were found in both countries. In Australia positive antibodies were identified in populations throughout most of the known range of B. marinus. Results were confirmed by immunofluorescence and immunoelectron microscopy where a characteristic staining pattern of 'ranaviruses' in infected cells was observed. Whilst a 'ranavirus(es)' has been isolated from populations of B. marinus in Venezuela, no virus has been isolated from Australian B. marinus populations. The significance of 'ranavirus' sero-positive B. marinus in Australia is discussed.

摘要

在澳大利亚和委内瑞拉，针对巨型海蟾蜍（Bufo marinus）体内抗“蛙病毒属病毒”的抗体进行了血清学调查。在这两个国家均发现了含有抗“蛙病毒属病毒”抗体的血清。在澳大利亚，在巨型海蟾蜍已知分布范围的大部分区域的种群中都鉴定出了阳性抗体。通过免疫荧光和免疫电子显微镜观察到感染细胞中“蛙病毒属病毒”具有特征性染色模式，从而证实了结果。虽然已从委内瑞拉的巨型海蟾蜍种群中分离出一种“蛙病毒属病毒”，但尚未从澳大利亚的巨型海蟾蜍种群中分离出病毒。本文讨论了澳大利亚巨型海蟾蜍血清学检测呈阳性的“蛙病毒属病毒”的意义。