Luchetti M, Stuani A, Castelli G, Marraro G
Servizio di Anestesia e Rianimazione, Azienda Ospedaliera, Fatebenefratelli e Oftalmico, Milano.
Minerva Anestesiol. 1998 Mar;64(3):75-81.
An efficient humidification system is expected to maintain fluid and easily drainable airway secretions. This study aims to compare the efficiency and safety of three humidification systems during prolonged mechanical ventilation.
Two-center, prospective, randomized study.
45 critically ill patients undergoing mechanical ventilation were included in the study and allocated to receive one of three humidification techniques: 1) Bennett Cascade water-bath humidifier (Bennett group); 2) Fisher & Paykel servocontrolled humidifier (F & P group); 3) HME Hygrobac DAR (HME group). Clinical and experimental observations were conducted for 3 to 7 consecutive days and included: body T degree, room T degree, inspired gas T degree, tracheal T degree, relative and absolute humidity, heat and water loss, airway secretion score, need for endotracheal saline instillation and incidence of ETT occlusion.
The HME group showed a lower temperature of inspired gases compared to the F & P group (p < 0.05); it also showed a lower absolute humidity compared to both Bennett and F & P groups (p < 0.05). A better airway secretion score was obtained in Bennett and F & P groups compared to the HME group (p < 0.01).
Passive humidification systems provided low degrees of humidity and temperature and could not maintain good secretions. Active systems appeared to satisfy the recommended standards and to allow fluid and easily drainable secretions.
高效的加湿系统应能保持气道分泌物呈液体状且易于排出。本研究旨在比较三种加湿系统在长时间机械通气期间的效率和安全性。
双中心、前瞻性、随机研究。
45例接受机械通气的重症患者纳入本研究,被分配接受三种加湿技术之一:1)贝内特级联水浴加湿器(贝内特组);2)费雪派克伺服控制加湿器(费雪派克组);3)热湿交换器(HME Hygrobac DAR,热湿交换器组)。连续3至7天进行临床和实验观察,包括:体温、室温、吸入气体温度、气管温度、相对湿度和绝对湿度、热量和水分流失、气道分泌物评分、气管内滴注生理盐水的需求以及气管插管堵塞的发生率。
与费雪派克组相比,热湿交换器组吸入气体温度较低(p < 0.05);与贝内特组和费雪派克组相比,其绝对湿度也较低(p < 0.05)。与热湿交换器组相比,贝内特组和费雪派克组气道分泌物评分更佳(p < 0.01)。
被动加湿系统提供的湿度和温度较低,无法保持良好的分泌物状态。主动加湿系统似乎符合推荐标准,并能使分泌物呈液体状且易于排出。