Zaccaria A, Giannoni M F, Speziale F, Maraglino C, Antonelli R, Rached H A, Fiorani P
I Cattedra di Chirurgia Vascolare, Università degli Studi di Roma, La Sapienza, Roma.
Minerva Cardioangiol. 1998 Mar;46(3):49-56.
On the basis of recent investigations, pulmonary embolism represents the third cause of death. If only hospitalized population over 65 years of age is considered, this pathology is quite the first cause of mortality. As deep venous thrombosis of the lower limbs represents the main cause of pulmonary embolism (90%), it should be right to suggest interruption of venous flow at caval level. The aim of this prospective report is to evaluate the efficacy of vena cava filter in pulmonary embolism prevention and the hemodynamic variations it can cause in the venous district of lower limbs.
137 definitive caval filters were positionated from 1989 to 1996. Average follow-up was 12.6 months. Patients were controlled at 2-7 days, 1 month and than every 6 months.
Filter perviousness was observed with Kaplan and Meyer's curve and it was 94.7%. There was pulmonary embolism in just 2 cases (1.4%). Filter perviousness was not depending on anticoagulant treatment.
In conclusion, this prospective experience underlines that: caval filter is effective in pulmonary embolism prophylaxis; there are not important hemodynamic alterations of inferior vena cava, below filter; anticoagulating treatment does not influence filter perviousness; there are not hemodynamic alterations after slight dislocations of caval filter; finally there is a direct relation between level of deep venous thrombosis and post-phlebitic manifestations.
根据最近的调查,肺栓塞是第三大致死原因。如果仅考虑65岁以上的住院患者,这种病症则是首要死因。由于下肢深静脉血栓形成是肺栓塞的主要原因(90%),因此建议在腔静脉水平阻断静脉血流是合理的。本前瞻性报告的目的是评估腔静脉滤器在预防肺栓塞方面的疗效以及它可能在下肢静脉区域引起的血流动力学变化。
1989年至1996年共放置了137个永久性腔静脉滤器。平均随访时间为12.6个月。在术后2 - 7天、1个月以及之后每6个月对患者进行检查。
采用Kaplan和Meyer曲线观察滤器的通畅率,为94.7%。仅2例(1.4%)发生了肺栓塞。滤器通畅率与抗凝治疗无关。
总之,这项前瞻性研究强调:腔静脉滤器在预防肺栓塞方面有效;滤器下方的下腔静脉不存在重要的血流动力学改变;抗凝治疗不影响滤器通畅率;腔静脉滤器轻微移位后不存在血流动力学改变;最后,深静脉血栓形成的程度与血栓形成后综合征之间存在直接关系。