Law L W, Chang K S, Ting R C
Proc Soc Exp Biol Med. 1976 Sep;152(4):585-8. doi: 10.3181/00379727-152-39445.
A cloned cell line H-11 (HP) derived from an MSV-induced neoplasm (a hemangiosarcoma) was found to possess virus-specific tumor rejection antigen(s). The specific nature of the immune response was established through the use of a polyoma virus-induced neoplasm no. 89 both in cross immunization and cross challenge experiments. Virus antigens or surface antigens associated with virus production are not responsible for tumor rejection since virus production could not be detected, nor were any viral fingerprints of MSV found by the several assays used.
从一株由MSV诱导产生的肿瘤（血管肉瘤）中克隆出的细胞系H-11（HP），被发现具有病毒特异性肿瘤排斥抗原。通过在交叉免疫和交叉攻击实验中使用一株由多瘤病毒诱导产生的肿瘤89号，确定了免疫反应的特异性。与病毒产生相关的病毒抗原或表面抗原并非肿瘤排斥的原因，因为检测不到病毒产生，而且使用的几种检测方法也未发现MSV的任何病毒印记。
