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严重的复方新诺明诱导的中性粒细胞减少伴CD4⁺/CD8⁺淋巴细胞比值逆转：对重组人粒细胞集落刺激因子（R-甲硫氨酸人粒细胞集落刺激因子）的反应

Severe bactrim-induced neutropenia with reversal of CD4+/CD8+ lymphocyte ratio: response to recombinant human granulocyte-colony stimulating factor (R-metHUG-CSF).

作者信息

Krishnan K, Krishnaswamy G

机构信息

Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-70622, USA.

出版信息

Clin Lab Haematol. 1998 Jun;20(3):187-8. doi: 10.1046/j.1365-2257.1998.00008.x.

DOI:10.1046/j.1365-2257.1998.00008.x
PMID:9681236
Abstract

A patient presented with severe bactrim-induced neutropenia with a reversed CD4+/CD8+ lymphocyte ratio. R-metHUG-CSF at 300 micrograms daily produced a dramatic neutrophil response and the therapy was discontinued after 2 weeks.

摘要

一名患者因服用复方新诺明出现严重中性粒细胞减少症，CD4⁺/CD8⁺淋巴细胞比值倒置。每日使用300微克的重组人粒细胞集落刺激因子（R-metHUG-CSF）产生了显著的中性粒细胞反应，2周后停止治疗。

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