Hirai T, Yamashita Y, Mukaida H, Kuwahara M, Inoue H, Toge T
Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan.
Surg Today. 1998;28(6):576-9. doi: 10.1007/s005950050187.
We investigated the relationship between postoperative complications and prognosis in esophageal cancer patients. Two hundred five patients with esophageal cancer were divided into three case groups. Group A (n = 100) consisted of cases without postoperative complications. Groups B (n = 58) and C (n = 47) consisted of cases with minor and major postoperative complications. The 5-year survival rates were 41.8%, 21.3%, and 20.2% in groups A, B, and C, respectively. There was a significant difference in the prognosis between groups A and B, and also between groups A and C. Any patients who died within 5 years without a relapse their cases were excluded from the study; the 5-year survival rates were 46.7%, 32.3%, and 22.5% in groups A, B, and C, respectively, with a significant difference between groups A and B. There were no significant differences between the three groups regarding the patient characteristics. These results therefore indicate that postoperative complications might contribute to a poor prognosis in cancer patients.
我们研究了食管癌患者术后并发症与预后之间的关系。205例食管癌患者被分为三个病例组。A组(n = 100)为无术后并发症的病例。B组(n = 58)和C组(n = 47)为有轻度和重度术后并发症的病例。A、B、C三组的5年生存率分别为41.8%、21.3%和20.2%。A组与B组之间以及A组与C组之间的预后存在显著差异。任何在5年内无复发而死亡的患者病例均被排除在研究之外;A、B、C三组的5年生存率分别为46.7%、32.3%和22.5%,A组与B组之间存在显著差异。三组患者的特征无显著差异。因此,这些结果表明术后并发症可能导致癌症患者预后不良。