Mortensen J, Carlsson K, Ohrström A
Department of Ophthalmology, County Council Hospital, Jönköping, Sweden.
J Cataract Refract Surg. 1998 Jul;24(7):893-8. doi: 10.1016/s0886-3350(98)80039-4.
To determine whether there is increased risk associated with excimer laser surgery of primary keratoconus.
Department of Ophthalmology, County Council Hospital, Ryhov, Jönköping, Sweden.
Twenty-four eyes in 23 patients with keratoconus had photorefractive keratectomy (PRK) to reduce the steepness of the cone. A VISX Twenty-Twenty B laser (193 nm) was used for the treatments. Spherical ablations, cylindrical ablations, or both were used. Patients were followed for a mean of 22 months (range 6 to 46 months).
Fourteen patients (58%) had improved visual acuity. Eleven (46%) could manage with only spectacles, and three (13%) were fitted with contact lenses to get adequate visual function. All treated corneas healed, and no acceleration of the keratoconus was seen.
No increased risk was associated with treating primary keratoconus with excimer laser PRK. We found that excimer laser surgery can improve vision and the ability to wear contact lenses, and it did not interfere with subsequent corneal transplantation surgery.
确定准分子激光手术治疗原发性圆锥角膜是否存在更高风险。
瑞典延雪平里霍夫郡议会医院眼科。
23例圆锥角膜患者的24只眼睛接受了准分子激光原位角膜磨镶术（PRK）以降低圆锥的陡峭程度。治疗使用VISX 20/20 B激光（193纳米）。采用了球面消融、柱面消融或两者结合的方式。患者平均随访22个月（范围6至46个月）。
14例患者（58%）视力提高。11例（46%）仅佩戴眼镜即可，3例（13%）佩戴隐形眼镜以获得足够的视觉功能。所有治疗的角膜均愈合，未观察到圆锥角膜进展加速。
准分子激光PRK治疗原发性圆锥角膜不存在更高风险。我们发现准分子激光手术可改善视力和佩戴隐形眼镜的能力，且不影响后续角膜移植手术。
