Fernández-Vega-Cueto L, Romano V, Zaldivar R, Gordillo C H, Aiello F, Madrid-Costa D, Alfonso J F
Fernández-Vega Ophthalmological Institute, Oviedo, Spain.
Department of Corneal and External Eye Diseases, The Royal Liverpool University Hospital, Liverpool, UK.
J Ophthalmol. 2017;2017:7589816. doi: 10.1155/2017/7589816. Epub 2017 Dec 18.
Keratoconus provides a decrease of quality of life to the patients who suffer from it. The treatment used as well as the method to correct the refractive error of these patients may influence on the impact of the disease on their quality of life. The purpose of this review is to describe the evidence about the conservative surgical treatment for keratoconus aiming to therapeutic and refractive effect. The visual rehabilitation for keratoconic corneas requires addressing three concerns: halting the ectatic process, improving corneal shape, and minimizing the residual refractive error. Cross-linking can halt the disease progression, intrastromal corneal ring segments can improve the corneal shape and hence the visual quality and reduce the refractive error, PRK can correct mild-moderate refractive error, and intraocular lenses can correct from low to high refractive error associated with keratoconus. Any of these surgical options can be performed alone or combined with the other techniques depending on what the case requires. Although it could be considered that the surgical option for the refracto-therapeutic treatment of the keratoconus is a reality, controlled, randomized studies with larger cohorts and longer follow-up periods are needed to determine which refractive procedure and/or sequence are most suitable for each case.
圆锥角膜会降低患者的生活质量。所采用的治疗方法以及矫正这些患者屈光不正的方式可能会影响该疾病对其生活质量的影响。本综述的目的是描述关于圆锥角膜保守手术治疗的证据,旨在实现治疗和屈光效果。圆锥角膜的视觉康复需要解决三个问题:阻止扩张进程、改善角膜形状以及将残余屈光不正降至最低。交联可以阻止疾病进展,角膜基质内环形片段可以改善角膜形状,从而提高视觉质量并减少屈光不正,准分子激光原位角膜磨镶术(PRK)可以矫正轻中度屈光不正,人工晶状体可以矫正与圆锥角膜相关的低至高屈光不正。根据具体病例的需要,这些手术选择中的任何一种都可以单独进行或与其他技术联合使用。尽管可以认为圆锥角膜屈光治疗的手术选择已成为现实,但仍需要进行有更大样本量和更长随访期的对照、随机研究,以确定哪种屈光手术和/或顺序最适合每个病例。