后囊膜混浊与钕:钇铝石榴石激光晶状体后囊切开术及肝素表面修饰人工晶状体
Posterior capsule opacification and neodymium: YAG capsulotomy with heparin-surface-modified intraocular lenses.
作者信息
Winther-Nielson A, Johansen J, Pedersen G K, Corydon L
机构信息
Department of Ophthalmology, Vejle Hospital, Denmark.
出版信息
J Cataract Refract Surg. 1998 Jul;24(7):940-4. doi: 10.1016/s0886-3350(98)80047-3.
PURPOSE
To compare the effect of heparin-surface-modified (HSM) and conventional unmodified poly(methyl methacrylate) (PMMA) intraocular lenses (IOLs) on the formation of posterior capsule opacification (PCO).
SETTING
Department of Ophthalmology, Vejle Hospital, Denmark.
METHODS
This prospective, randomized, double-blind study comprised 250 eyes of 246 patients who had uneventful extracapsular cataract extraction in otherwise healthy eyes with implantation of a biconvex IOL or a convex-plano lens with a continuous laser ridge. Patients were examined once a year for 3 years, at which time the degree of PCO was recorded. A neodymium:YAG laser capsulotomy was performed if certain criteria were met.
RESULTS
The incidence of PCO was statistically significantly higher in eyes with an HSM convex-plano laser-ridge IOL than in those with an unmodified convex-plano lens (P < .005). There were no significant differences between any other groups.
CONCLUSION
The incidence of PCO was higher in eyes with an HSM convex-plano IOL with a laser ridge.
目的
比较肝素表面改性（HSM）和传统未改性聚甲基丙烯酸甲酯（PMMA）人工晶状体（IOL）对后囊膜混浊（PCO）形成的影响。
设置
丹麦韦勒医院眼科。
方法
这项前瞻性、随机、双盲研究纳入了246例患者的250只眼，这些患者在其他方面健康的眼睛中进行了顺利的囊外白内障摘除术，并植入了双凸IOL或带有连续激光脊的凸平IOL。患者每年接受一次检查，为期3年，届时记录PCO的程度。如果符合某些标准，则进行钕：YAG激光囊切开术。
结果
使用HSM凸平激光脊IOL的眼睛中PCO的发生率在统计学上显著高于使用未改性凸平IOL的眼睛（P <.005）。其他任何组之间均无显著差异。
结论
带有激光脊的HSM凸平IOL的眼睛中PCO的发生率更高。
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