Dudkin A O, Zamuraev I N
Petersburg Nuclear Physics Institute, Department of Radiation and Molecular Biophysics, Russian Academy of Science.
Radiats Biol Radioecol. 1998 May-Jun;38(3):462-7.
The influence of X-ray impulses (dose 0.003 cGy, longitudity 10 ns) and EM impulses (induction 0.003 mT) on sciatic nerve regeneration in mice after crush lesion was studied. Limb jerk amplitude at electric stimulation of nerve and postural reflex in thin rod in X + EM and EM groups were restored within 13th days after lesion, in control group within 15 days (p < 0.05). The beginning of repairing of postural reflex was early in X + EM group than on EM group, rehabilitation of limb jerk amplitude--in EM group. Histological examination demonstrated that myelin degenerated in EM group more rapidly as compared with X + EM and control groups. This data suppose different effects of EM and X + EM impulses on nerve-regenerating processes.
研究了X射线脉冲(剂量0.003 cGy,时长10 ns)和电磁脉冲(感应强度0.003 mT)对小鼠坐骨神经挤压损伤后再生的影响。在损伤后第13天,X + EM组和EM组在神经电刺激时的肢体抽搐幅度以及在细杆上的姿势反射恢复,而对照组在第15天恢复(p < 0.05)。X + EM组姿势反射修复开始时间早于EM组,肢体抽搐幅度的恢复则是EM组更好。组织学检查表明,与X + EM组和对照组相比,EM组髓鞘退化更快。这些数据表明电磁脉冲和X + EM脉冲对神经再生过程有不同影响。