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正常发声和功能性发声障碍中声带振动的有限元建模:对声带小结发病机制的启示

Finite element modeling of vocal fold vibration in normal phonation and hyperfunctional dysphonia: implications for the pathogenesis of vocal nodules.

作者信息

Jiang J J, Diaz C E, Hanson D G

机构信息

Department of Otolaryngology-Head and Neck Surgery, Northwestern University Medical School, Chicago, Illinois 60611-3008, USA.

出版信息

Ann Otol Rhinol Laryngol. 1998 Jul;107(7):603-10. doi: 10.1177/000348949810700711.

DOI:10.1177/000348949810700711
PMID:9682857
Abstract

A computer model of the vocal fold was developed using finite element modeling technology for studying mechanical stress distribution over vibrating vocal fold tissue. In a simulated normal phonation mode, mechanical stress was found to be lowest at the midpoint of the vocal fold and highest at tendon attachments. However, when other modes predominated, high mechanical stress could occur at the midpoint of the vocal folds. When a vocal fold mass was modeled, high shearing stress occurred at the base of the modeled vocal fold mass, suggesting that the presence of a vocal nodule or polyp is associated with high mechanical stress at the margins of the mass. This finding supports a hypothesis that mechanical intraepithelial stress plays an important role in the development of vocal nodules, polyps, and other lesions that are usually ascribed to hyperfunctional dysphonia.

摘要

利用有限元建模技术开发了一种声带计算机模型,用于研究振动声带组织上的机械应力分布。在模拟的正常发声模式下,发现机械应力在声带中点处最低,在肌腱附着处最高。然而,当其他模式占主导时,声带中点处可能会出现高机械应力。当对声带肿物进行建模时,在建模的声带肿物底部出现了高剪切应力,这表明声带小结或息肉的存在与肿物边缘的高机械应力有关。这一发现支持了一种假说,即上皮内机械应力在声带小结、息肉和其他通常归因于功能亢进性发音障碍的病变的发展中起重要作用。

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