Jenni R, Berger-Bächi B
Institute of Medical Microbiology, University of Zürich, Gloriastrasse 32, Postfach, CH-8028 Zürich, Switzerland.
Arch Microbiol. 1998 Sep;170(3):171-8. doi: 10.1007/s002030050630.
A series of mec transformants of Staphylococcus aureus strain NCTC8325 were analysed for alterations in wall teichoic acid and lipoteichoic acid. Although the methicillin resistance determinant alters the autolytic behaviour of S. aureus, it had no effects on the cellular content, chain length, and alanine substitution of the lipoteichoic acid, or on the wall teichoic acid content and composition. However, independently of the presence or absence of the methicillin resistance determinant, level of methicillin resistance, or autolytic behaviour, a correlation was found between a 25% reduced cell wall phosphate content and either loss of prophages phi11 and 13 or a 30-kb deletion in the chomosmal SmaI-F fragment adjacent to the prophage φ11 attachment site.
对金黄色葡萄球菌菌株NCTC8325的一系列mec转化体进行了分析，以研究其壁磷壁酸和脂磷壁酸的变化。尽管耐甲氧西林决定簇改变了金黄色葡萄球菌的自溶行为，但它对脂磷壁酸的细胞含量、链长度和丙氨酸取代，或对壁磷壁酸的含量和组成均无影响。然而，无论是否存在耐甲氧西林决定簇、耐甲氧西林水平或自溶行为，都发现细胞壁磷酸盐含量降低25%与噬菌体phi11和13的缺失或与噬菌体phi11附着位点相邻的染色体SmaI-F片段中的30 kb缺失之间存在相关性。
