Butt Z, Kaufman D, McNab A, McKelvie P
Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Eye (Lond). 1998;12 ( Pt 2):285-90. doi: 10.1038/eye.1998.66.
Ocular cicatricial pemphigoid is a slowly progressive disease of mucous membranes and skin of unknown but presumed autoimmune aetiology. We describe eight cases of presumed drug-induced cicatrising conjunctival changes simulating ocular cicatricial pemphigoid, following the chronic use of topical glaucoma medication. In three of four patients who underwent conjunctival biopsy of the inferior fornix, this revealed histopathological changes similar to ocular cicatricial pemphigoid.
瘢痕性类天疱疮是一种病因不明但推测为自身免疫性的、累及黏膜和皮肤的缓慢进展性疾病。我们描述了8例在长期使用局部青光眼药物后出现的疑似药物性瘢痕性结膜改变，这些改变酷似瘢痕性类天疱疮。在接受下穹窿结膜活检的4例患者中的3例，活检显示出与瘢痕性类天疱疮相似的组织病理学改变。
