Viswanath Y K, Griffiths C D
Department of Surgery, General Hospital, Newcastle upon Tyne, UK.
Postgrad Med J. 1998 Apr;74(870):216-9. doi: 10.1136/pgmj.74.870.216.
Pseudomembranous enterocolitis is an inflammatory bowel disorder caused by Clostridium difficile toxins. Classical presentation includes abdominal pain, pyrexia, diarrhoea and leucocytes. The management is mainly conservative but in extreme cases surgery is necessary. Resectional procedures (colectomy) carry a better prognosis than diversion procedures (colostomy). A careful history, a high index of suspicion, and early diagnosis and treatment would reduce the associated morbidity and mortality of this condition. The aetiopathogenesis, pathology, clinical presentation, diagnosis, differential diagnosis, complications, medical and surgical management are reviewed, and three case reports briefly discussed. A management algorithm is also suggested.
伪膜性小肠结肠炎是一种由艰难梭菌毒素引起的炎症性肠病。典型表现包括腹痛、发热、腹泻和白细胞增多。治疗主要是保守治疗，但在极端情况下需要手术。切除手术（结肠切除术）的预后比改道手术（结肠造口术）更好。仔细的病史询问、高度的怀疑指数以及早期诊断和治疗将降低该疾病的相关发病率和死亡率。本文对其病因发病机制、病理、临床表现、诊断、鉴别诊断、并发症、内科和外科治疗进行了综述，并简要讨论了三例病例报告。还提出了一种治疗算法。
