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Preoperative radiation therapy and chemotherapy for adenocarcinoma of the pancreas.

作者信息

Hoffman J P, Pendurthi T K, Ross E, Yeung R S

机构信息

Department of Surgery, Fox Chase Cancer Center, Philadelphia, PA 1911, USA.

出版信息

Hepatogastroenterology. 1998 May-Jun;45(21):634-7.

PMID:9684108
Abstract

Since preoperative radiation therapy combined with chemotherapy (CTRT) was first performed in 1986 for patients with pancreatic adenocarcinoma, there have been several reported experiences with varying drugs and radiotherapy regimens. We describe those experiences and contrast them to a series of patients treated at our institution with resectional surgery before CTRT. Finally, the current role of preoperative CTRT in the therapy of pancreatic adenocarcinoma is proposed.

摘要

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Primary resection versus neoadjuvant chemoradiation followed by resection for locally resectable or potentially resectable pancreatic carcinoma without distant metastasis. A multi-centre prospectively randomised phase II-study of the Interdisciplinary Working Group Gastrointestinal Tumours (AIO, ARO, and CAO).
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