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恶性食管狭窄的姑息治疗:塑料支架与金属支架的应用经验

Palliative treatment of malignant esophageal stenosis: experience with plastic versus metal stents.

作者信息

Schumacher B, Lübke H, Frieling T, Haussinger D, Niederau C

机构信息

Department of Gastroenterology, Hepatology and Infectiology, Heinrich-Heine-University of Düsseldorf, Germany.

出版信息

Hepatogastroenterology. 1998 May-Jun;45(21):755-60.

PMID:9684128
Abstract

BACKGROUND/AIMS: We report on the palliative treatment of 44 patients with malignant dysphagia by placement of plastic (Celestin tubes, n = 24) vs metal stents (Wall stents, Nitinol stents, Gianturco stents, n = 20).

METHODOLOGY

Prior to stent insertion, esophageal stenosis was dilated stepwise to 16 mm (plastic tube) and to 10 mm (metal stent).

RESULTS

Stent insertion was technically successful in all cases and led to a reduction of dysphagia. Risk of perforation was comparable in both groups (n = 1 in each group). Most of the plastic stents were placed when the tumor was localized in the proximal part of the esophagus close to the upper esophageal sphincter, when esophageal-bronchial fistula was present and in the risk of fistula development after radiation. During follow-up, tumor ingrowth (TI) and stent migration (SM) were the major complications. Whereas tumor ingrowth predominantly occurred in metal stents (TI after 6 weeks, 45% vs. SM, 10%) that required repeated argon beamer therapy, tube migration and bolus impaction (BI) often occurred in patients with plastic stents (TI, 0% vs. SM, 16%; BI, 4%).

CONCLUSIONS

The findings of the study suggest that the decision whether plastic tubes or metal stents used should be taken individually considering tumor localization, axis deviation and the presence of esophago-respiratory fistulas. When stepwise dilation of malignant stenoses is performed carefully, perforation risk appears not to be different between placement of plastic prostheses and metal stents.

摘要

背景/目的:我们报告了44例恶性吞咽困难患者采用置入塑料支架(塞莱斯坦管,24例)与金属支架(沃尔支架、镍钛诺支架、吉安图尔科支架,20例)进行姑息治疗的情况。

方法

在置入支架前,将食管狭窄逐步扩张至16毫米(塑料支架)和10毫米(金属支架)。

结果

所有病例的支架置入技术均成功,并减轻了吞咽困难。两组的穿孔风险相当(每组各1例)。大多数塑料支架是在肿瘤位于食管近端靠近食管上括约肌处、存在食管支气管瘘以及放疗后有瘘形成风险时置入的。在随访期间,肿瘤向内生长(TI)和支架迁移(SM)是主要并发症。肿瘤向内生长主要发生在金属支架中(6周后TI为45%,而SM为10%),这需要重复氩离子束治疗,而塑料支架患者常发生管迁移和团块嵌塞(BI)(TI为0%,而SM为16%;BI为4%)。

结论

该研究结果表明,应根据肿瘤定位、轴线偏差和食管呼吸道瘘的情况,个体化决定使用塑料支架还是金属支架。当仔细对恶性狭窄进行逐步扩张时,置入塑料假体和金属支架的穿孔风险似乎没有差异。

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