聚酯纤维织物表面的内皮细胞在体外表现出促凝血表型。
Endothelial cells lining polyester fabric express pro-coagulant phenotype in vitro.
作者信息
Rémy M, Bareille R, Villars F, Rouais F, Gorodkov A, Bordenave L
机构信息
INSERM U 443, Université Victor Segalen Boreaux, France.
出版信息
Med Biol Eng Comput. 1998 Mar;36(2):256-7. doi: 10.1007/BF02510755.
PMID:9684472
Abstract
The paper deals with the in vitro assessment of endothelial cell (EC) phenotype covering an albumin- and chitosan-coated polyester fabric and shows that resting ECs express a pro-coagulant phenotype by releasing a high von Willebrand factor level and expressing low thrombomodulin surface activity, despite maintaining an adequate response to stimulating agents.
摘要
该论文涉及对覆盖白蛋白和壳聚糖的聚酯织物上内皮细胞（EC）表型的体外评估，结果表明，尽管静息内皮细胞对刺激剂仍保持充分反应，但通过释放高水平的血管性血友病因子并表达低水平的血栓调节蛋白表面活性，呈现促凝血表型。
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