Chen C T, Hsu H C, Liu S M, Ho C H
Department of Medicine, Veterans General Hospital-Taipei, National Yang-Ming University, Taiwan, ROC.
Zhonghua Yi Xue Za Zhi (Taipei). 1998 Jun;61(6):367-70.
Immunoglobulin D (IgD) multiple myeloma is a rare disorder with a poor prognosis. We herein report a case of IgD myeloma presenting with renal failure and bicytopenia. A bone marrow biopsy specimen showed infiltration of homogeneous plasma cells, which stained positively for IgD and light chains. We review the literature and discuss the clinical manifestations, diagnosis and treatment strategy for this rare tumor.
免疫球蛋白D(IgD)多发性骨髓瘤是一种预后较差的罕见疾病。我们在此报告一例表现为肾衰竭和双血细胞减少的IgD骨髓瘤病例。骨髓活检标本显示均匀的浆细胞浸润,其IgD和轻链染色呈阳性。我们回顾文献并讨论这种罕见肿瘤的临床表现、诊断和治疗策略。