[多元醇途径在糖尿病性白内障形成中的作用]
[The role of polyol pathways in formation of diabetic cataracts].
作者信息
Sabasiński K, Andrzejewska-Buczko J
机构信息
Katedry i Kliniki Okulistyki AM w Białymstoku.
出版信息
Klin Oczna. 1997;99(6):401-4.
PMID:9685789
Abstract
The authors present current knowledge concerning the role of polyols in the formation of cataract in diabetic patients. Sugar alcohols are formed in lens as a consequence of glucose conversion in the sorbitol pathway. The pharmacological modulation of this process by the application of aldose reductase inhibitors are also discussed.
摘要
作者介绍了有关多元醇在糖尿病患者白内障形成中作用的当前知识。糖醇是通过山梨醇途径中葡萄糖的转化在晶状体中形成的。还讨论了应用醛糖还原酶抑制剂对这一过程的药理调节作用。
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