Sabasiński K, Andrzejewska-Buczko J
Katedry i Kliniki Okulistyki AM w Białymstoku.
Klin Oczna. 1997;99(6):401-4.
The authors present current knowledge concerning the role of polyols in the formation of cataract in diabetic patients. Sugar alcohols are formed in lens as a consequence of glucose conversion in the sorbitol pathway. The pharmacological modulation of this process by the application of aldose reductase inhibitors are also discussed.
作者介绍了有关多元醇在糖尿病患者白内障形成中作用的当前知识。糖醇是通过山梨醇途径中葡萄糖的转化在晶状体中形成的。还讨论了应用醛糖还原酶抑制剂对这一过程的药理调节作用。