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[1995年古巴由B19细小病毒引起的发热和皮疹暴发的病毒学诊断]

[Virological diagnosis of an outbreak of fever and rashes caused by parvovirus B19, Cuba, 1995].

作者信息

Guzmán M G, Rosario D, Rodríguez M E, Alvarez M, Rodríguez R, Oropesa S, Laferté J, Resik S

机构信息

Instituto de Medicina Tropical Pedro Kourí.

出版信息

Rev Cubana Med Trop. 1997;49(1):14-20.

PMID:9685954
Abstract

The results obtained in the study of an a outbreak of fever and rash occurred in Havana City in March, 1995, are reported. Dengue, measles, rubella, herpes simplex, and Epstein Barr were discarded as causal agents of the outbreak in the samples of 35 patients. Parvovirus B19 was identified as the causing agent of the outbreak by the detection of IgM antibodies and the polymerase chain reaction technique (PCR). The infection produced by this agent was confirmed in 14/18 samples (77.7%) by some of the techniques used. This study makes reference to the first outbreak of Parvovirus B19 that was proved in Cuba.

摘要

本文报告了1995年3月在哈瓦那市发生的一次发热伴皮疹疫情的研究结果。在35名患者的样本中,登革热、麻疹、风疹、单纯疱疹和EB病毒被排除为该疫情的病原体。通过检测IgM抗体和聚合酶链反应技术(PCR),确定细小病毒B19为此次疫情的病原体。在所使用的一些技术中,14/18份样本(77.7%)证实了该病原体产生的感染。本研究提及了古巴首次证实的细小病毒B19疫情。

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