Triglia J M, Nicollas R, Roman S, Dessi P
Unité d'ORL Pédiatrique, Fédération ORL, Hôpital de la Timone, Marseille.
Ann Otolaryngol Chir Cervicofac. 1997;114(7-8):267-71.
Nasosinusal polyposis in the pediatric population is uncommon and its etiology is unclear. In this eleven-year retrospective study, we describe the etiologic features and evaluate the effectiveness of endoscopic sinus surgery in 49 children. Patients were divided into three groups according to whether nasosinusal polyposis was either isolated (n = 14), or associated with either asthma (n = 5) or cystic fibrosis (n = 30). An allergy was present in 10% of patients with isolated polyposis, 80% of patients with polyposis associated with asthma, and 19% of patients with polyposis associated with cystic fibrosis. The indications for surgery were disabling symptoms, specially chronic nasal obstruction, rhinorrhea and mouth breathing, and failure to respond to medical treatment. No surgical complications were encountered. Most patients reported improvement in quality of life with reduction of nasal obstruction in 83% of cases and rhinorrhea in 61%. Minor asymptomatic recurrence (i.e. a few micropolyp localized on the roof of the ethmoid cavity) was observed in 22.7% of the cases in this series, and major recurrence with the same functional symptoms as before surgery in 13.6%. However, recurrences were higher in patients with cystic fibrosis, since minor recurrence with no clinical manifestation was observed in 28.6% of cases and major recurrence in 17.8%. Endoscopic sinus surgery must be decided in collaboration with the pediatric and pulmonary physicians, and must be performed skillfully. With a mean follow-up of 4 years, results in this series are encouraging.
小儿鼻窦息肉病并不常见,其病因尚不清楚。在这项为期11年的回顾性研究中,我们描述了49例儿童的病因特征,并评估了鼻内镜鼻窦手术的有效性。根据鼻窦息肉病是孤立性的(n = 14)、还是与哮喘(n = 5)或囊性纤维化(n = 30)相关,将患者分为三组。孤立性息肉病患者中有10%存在过敏,息肉病合并哮喘患者中有80%存在过敏,息肉病合并囊性纤维化患者中有19%存在过敏。手术指征为致残性症状,特别是慢性鼻塞、流涕和张口呼吸,以及药物治疗无效。未发生手术并发症。大多数患者报告生活质量有所改善,83%的病例鼻塞减轻,61%的病例流涕减轻。在本系列病例中,22.7%的病例观察到轻微无症状复发(即筛窦腔顶部有一些微息肉),13.6%的病例出现与手术前相同功能症状的严重复发。然而,囊性纤维化患者的复发率更高,28.6%的病例观察到无临床表现的轻微复发,17.8%的病例出现严重复发。鼻内镜鼻窦手术必须与儿科和肺科医生共同决定,并且必须熟练进行。平均随访4年,本系列结果令人鼓舞。