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[上颌窦腺样囊性癌伴颅内侵犯。结合一例病例对文献的综述]

[Adenoid cystic carcinomas of the maxillary sinus with intracranial invasion. Review of the literature, apropos of a case].

作者信息

Nuti C, Durand M, Duthel R, Seguin P, Prades J M, Mosnier J F, Brunon J

机构信息

Service de Neurochirurgie, Hôpital de Bellevue, CHU, Saint-Etienne.

出版信息

Neurochirurgie. 1997;43(5):314-8.

PMID:9686237
Abstract

We report a case of adenocystic carcinoma (cylindroma) of the maxillary sinus with intracranial extension in a 35-year-old man with no previous clinical history. The patient underwent primary neurological and maxillofacial surgery. He then developed two successive recurrences of the tumor in the temporo-parietal area of the brain treated by surgery and radiotherapy for the first one and surgery alone for the second. The patient finally died 4 years and 2 months after the diagnosis. Adenoid cystic carcinomas are malignant epithelial neoplasms that arise mainly from salivary glands (14% of the salivary tumors), and less frequently from other structures. Their histological pattern can be either tubular, cribriform or solid, with different prognosis. They invade local areas (perineural spaces) and also metastasize to the lung, liver, bone, regional lymph nodes. Treatment mainly consists in combined surgery and radiation therapy. Chemotherapy might be also used.

摘要

我们报告一例35岁男性上颌窦腺囊腺癌(圆柱瘤)伴颅内侵犯,此前无相关临床病史。患者接受了初次神经外科和颌面外科手术。随后,肿瘤在脑颞顶区先后两次复发,第一次复发采用手术和放疗治疗,第二次仅行手术治疗。患者最终在确诊后4年零2个月死亡。腺样囊性癌是主要起源于唾液腺的恶性上皮性肿瘤(占唾液腺肿瘤的14%),较少起源于其他结构。其组织学模式可为管状、筛状或实性,预后不同。它们侵犯局部区域(神经周围间隙),也可转移至肺、肝、骨、区域淋巴结。治疗主要包括手术和放疗联合。也可能使用化疗。

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