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Investigation of the copper binding sites in the Menkes disease protein, ATP7A. SSIEM Award. Society of the Study of Inborn Errors of Metabolism.

作者信息

Jensen P Y, Bonander N, Karlsson B G, Horn N, Tümer Z, Farver O

机构信息

Department of Analytical and Pharmaceutical Chemistry, Royal Danish School of Pharmacy, Copenhagen, Denmark.

出版信息

J Inherit Metab Dis. 1998 Jun;21(3):195-8. doi: 10.1023/a:1005331130245.

DOI:10.1023/a:1005331130245
PMID:9686355
Abstract
摘要

相似文献

1
Investigation of the copper binding sites in the Menkes disease protein, ATP7A. SSIEM Award. Society of the Study of Inborn Errors of Metabolism.门克斯病蛋白ATP7A中铜结合位点的研究。SSIEM奖。先天性代谢缺陷研究学会。
J Inherit Metab Dis. 1998 Jun;21(3):195-8. doi: 10.1023/a:1005331130245.
2
A single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasis.一种单一的PDZ结构域蛋白与门克斯铜ATP酶ATP7A相互作用。一种与铜稳态有关的新蛋白。
J Biol Chem. 2005 Sep 30;280(39):33270-9. doi: 10.1074/jbc.M505889200. Epub 2005 Jul 28.
3
A numerical investigation into possible mechanisms by that the A629P mutant of ATP7A causes Menkes Disease.对 ATP7A 的 A629P 突变导致 Menkes 病的可能机制进行数值研究。
Phys Chem Chem Phys. 2010 Oct 7;12(37):11390-7. doi: 10.1039/c003568h. Epub 2010 Aug 16.
4
Copper transport and its alterations in Menkes and Wilson diseases.铜转运及其在门克斯病和威尔逊病中的改变。
Biochim Biophys Acta. 1997 Feb 27;1360(1):3-16. doi: 10.1016/s0925-4439(96)00064-6.
5
Molecular mechanisms of copper homeostasis.铜稳态的分子机制。
Biochem Biophys Res Commun. 1999 Aug 2;261(2):225-32. doi: 10.1006/bbrc.1999.1073.
6
[The proposed role of the ceruloplasmin receptor and Cu2+-transferring Menkes ATPase in copper metabolism in mammals].[血浆铜蓝蛋白受体和铜转运的门克斯ATP酶在哺乳动物铜代谢中的假定作用]
Mol Biol (Mosk). 1999 Mar-Apr;33(2):287-90.
7
Intracellular localization and loss of copper responsiveness of Mnk, the murine homologue of the Menkes protein, in cells from blotchy (Mo blo) and brindled (Mo br) mouse mutants.斑驳（Mo blo）和虎斑（Mo br）小鼠突变体细胞中，门克斯蛋白的小鼠同源物Mnk的细胞内定位及铜反应性丧失。
Hum Mol Genet. 1999 Jun;8(6):1069-75. doi: 10.1093/hmg/8.6.1069.
8
Menkes and Wilson diseases.门克斯病和威尔逊病。
Adv Genet. 1995;33:233-53. doi: 10.1016/s0065-2660(08)60335-1.
9
A novel frameshift mutation in exon 23 of ATP7A (MNK) results in occipital horn syndrome and not in Menkes disease.ATP7A（MNK）第23外显子中的一种新型移码突变导致枕角综合征，而非门克斯病。
Am J Hum Genet. 2001 Aug;69(2):420-7. doi: 10.1086/321290. Epub 2001 Jun 26.
10
Molecular mechanisms of copper metabolism and the role of the Menkes disease protein.铜代谢的分子机制及门克斯病蛋白的作用
J Biochem Mol Toxicol. 1999;13(2):93-106. doi: 10.1002/(sici)1099-0461(1999)13:2<93::aid-jbt5>3.0.co;2-3.

引用本文的文献

1
Posttranslational regulation of copper transporters.铜转运蛋白的翻译后调控。
J Biol Inorg Chem. 2010 Jan;15(1):37-46. doi: 10.1007/s00775-009-0592-7. Epub 2009 Oct 8.
2
Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes.威尔逊病和门克斯病的分子发病机制：突变与分子缺陷及疾病表型的相关性
J Med Genet. 2007 Nov;44(11):673-88. doi: 10.1136/jmg.2007.052746. Epub 2007 Aug 23.

本文引用的文献

1
Structures of the reduced and mercury-bound forms of MerP, the periplasmic protein from the bacterial mercury detoxification system.来自细菌汞解毒系统的周质蛋白MerP的还原形式和汞结合形式的结构。
Biochemistry. 1997 Jun 10;36(23):6885-95. doi: 10.1021/bi9631632.
2
Immunocytochemical localization of the Menkes copper transport protein (ATP7A) to the trans-Golgi network.门克斯铜转运蛋白（ATP7A）在反式高尔基体网络中的免疫细胞化学定位。
Hum Mol Genet. 1997 Mar;6(3):409-16. doi: 10.1093/hmg/6.3.409.
3
Copper transport and its alterations in Menkes and Wilson diseases.
铜转运及其在门克斯病和威尔逊病中的改变。
Biochim Biophys Acta. 1997 Feb 27;1360(1):3-16. doi: 10.1016/s0925-4439(96)00064-6.
4
Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking.配体调控的门克斯铜P型ATP酶外排泵从高尔基体到质膜的转运：一种新型的调控运输机制。
EMBO J. 1996 Nov 15;15(22):6084-95.
5
ATP-dependent copper transporter, in the Golgi apparatus of rat hepatocytes, transports Cu(II) not Cu(I).依赖ATP的铜转运蛋白在大鼠肝细胞的高尔基体中转运的是Cu(II)而非Cu(I)。
Am J Physiol. 1996 Nov;271(5 Pt 1):G741-6. doi: 10.1152/ajpgi.1996.271.5.G741.
6
Biochemical characterization and intracellular localization of the Menkes disease protein.门克斯病蛋白的生化特性及细胞内定位
Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14030-5. doi: 10.1073/pnas.93.24.14030.
7
Menkes disease: recent advances and new insights into copper metabolism.门克斯病：铜代谢的最新进展与新见解
Ann Med. 1996 Apr;28(2):121-9. doi: 10.3109/07853899609092936.