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[老年人脂质代谢紊乱的治疗]

[Treatment of lipid metabolism disorders in the elderly].

作者信息

Mizera W, Grzeszczak W

机构信息

Oddziału Wewnetrznego III Zespołu Opieki Zdrowotnej w Czeladzi.

出版信息

Wiad Lek. 1998;51 Suppl 2:52-7.

PMID:9686534
Abstract

Positive correlation between cholesterol concentration and morbidity of circulatory system diseases is not questioned and has a large evidence in literature. Aging is associated with increasing mean concentration of serum lipids, especially LDL cholesterol fraction. But the risk of coronary heart disease in patients at advanced age with hypercholesterolemia is less significant than in younger ones. In the therapy of hyperlipidemia the usage of hypolipemic drugs (statin) is not practical recommended in the elderly. Possible usage of these drugs should not reduce the comfort of life. Diet is an alternative and also effective method of lipid-lowering therapy.

摘要

胆固醇浓度与循环系统疾病发病率之间的正相关关系毋庸置疑,且在文献中有大量证据。衰老与血清脂质平均浓度升高有关,尤其是低密度脂蛋白胆固醇部分。但高龄高胆固醇血症患者患冠心病的风险比年轻患者小。在高脂血症治疗中,不实际推荐老年人使用降血脂药物(他汀类药物)。这些药物的可能使用不应降低生活舒适度。饮食是一种替代且有效的降脂治疗方法。

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引用本文的文献

1
Statin Therapy in Very Old Patients: Lights and Shadows.老年患者的他汀类药物治疗:光明与阴影
Front Cardiovasc Med. 2021 Nov 29;8:779044. doi: 10.3389/fcvm.2021.779044. eCollection 2021.

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