Pasic S, Lilic D, Pejnovic N, Vojvodic D, Simic R, Abinun M
Department of Paediatric Immunology, Mother and Child Health Institute, Belgrade, Yugoslavia.
Acta Paediatr. 1998 Jun;87(6):702-4. doi: 10.1080/080352598750014166.
Disseminated Bacillus Calmette-Guérin infection occurs in few well-defined immunodeficiencies, such as severe combined immunodeficiency, chronic granulomatous disease and paediatric acquired immunodeficiency syndrome. This severe complication of immunization against tuberculosis has been lethal in the majority of children who had primary immunodeficiency. Our patient, a 9-y-old girl with hyperimmunoglobulin E syndrome developed disseminated Bacillus Calmette-Guérin infection in infancy. Patients with hyperimmunoglobulin E syndrome (HIES) are susceptible to serious staphylococcal and fungal infections. Disseminated Bacillus Calmette-Guérin infection has not previously been reported in this rare immunodeficiency.
播散性卡介苗感染发生于少数明确的免疫缺陷病，如严重联合免疫缺陷、慢性肉芽肿病和儿童获得性免疫缺陷综合征。这种结核病免疫接种的严重并发症在大多数原发性免疫缺陷儿童中是致命的。我们的患者是一名9岁患有高免疫球蛋白E综合征的女孩，在婴儿期发生了播散性卡介苗感染。高免疫球蛋白E综合征（HIES）患者易发生严重的葡萄球菌和真菌感染。此前在这种罕见的免疫缺陷病中尚未有播散性卡介苗感染的报道。
