播散性卡介苗感染概述：文献综述
Disseminated Bacille Calmette-Guérin infection at a glance: a mini review of the literature.
作者信息
Hassanzad Maryam, Valinejadi Ali, Darougar Sepideh, Hashemitari Seyed Karen, Velayati Ali Akbar
机构信息
Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
出版信息
Adv Respir Med. 2019;87(4):239-242. doi: 10.5603/ARM.2019.0040.
INTRODUCTION
Immunodeficient children are at a high risk of disseminated Bacillus Calmette-Guérin [BCG] infection. We assessed the literature on clinical manifestations of BCGosis in children with specific primary immunodeficiencies.
MATERIAL AND METHODS
We conducted a systematic review of clinical practice articles by searching Medline, PubMed, Embase, Scopus, Web of Science and Google Scholar from their inception to date.
RESULTS
Thirty-seven articles were included regarding BCG vaccination and its dissemination in children with primary immunodeficiencies. Articles on dissemination after intravesicular BCG were excluded from the study.
CONCLUSIONS
Since disseminated BCG vaccination may be the first manifestation of a primary immunodeficiency disease, a comprehensive search for immunological defects in children developing these problems after BCG vaccination seems rational.
引言
免疫缺陷儿童发生播散性卡介苗（BCG）感染的风险很高。我们评估了有关特定原发性免疫缺陷儿童卡介苗病临床表现的文献。
材料与方法
我们通过检索Medline、PubMed、Embase、Scopus、科学网和谷歌学术从创刊至今的临床实践文章进行了系统评价。
结果
纳入了37篇关于卡介苗接种及其在原发性免疫缺陷儿童中播散的文章。膀胱内卡介苗接种后播散的文章被排除在研究之外。
结论
由于播散性卡介苗接种可能是原发性免疫缺陷疾病的首发表现，对卡介苗接种后出现这些问题的儿童进行全面的免疫缺陷筛查似乎是合理的。
Zotero 插件