Riechmann J L, Meyerowitz E M
Division of Biology, California Institute of Technology, Pasadena 91125, USA.
Biol Chem. 1998 Jun;379(6):633-46. doi: 10.1515/bchm.1998.379.6.633.
AP2 (APETALA2) and EREBPs (ethylene-responsive element binding proteins) are the prototypic members of a family of transcription factors unique to plants, whose distinguishing characteristic is that they contain the so-called AP2 DNA-binding domain. AP2/ REBP genes form a large multigene family, and they play a variety of roles throughout the plant life cycle: from being key regulators of several developmental processes, like floral organ identity determination or control of leaf epidermal cell identity, to forming part of the mechanisms used by plants to respond to various types of biotic and environmental stress. The molecular and biochemical characteristics of the AP2/EREBP transcription factors and their diverse functions are reviewed here, and this multigene family is analyzed within the context of the Arabidopsis thaliana genome sequence project.
AP2(APETALA2)和EREBP(乙烯响应元件结合蛋白)是植物特有的转录因子家族的典型成员,其显著特征是它们含有所谓的AP2 DNA结合结构域。AP2/REBP基因形成一个庞大的多基因家族,它们在植物生命周期中发挥着多种作用:从作为几个发育过程的关键调节因子,如控制花器官特征或叶表皮细胞特征,到构成植物应对各种生物和环境胁迫机制的一部分。本文综述了AP2/EREBP转录因子的分子和生化特性及其多样功能,并在拟南芥基因组序列计划的背景下对这个多基因家族进行了分析。