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腹主动脉重建术后缺血性结肠炎的发病率:一项前瞻性研究。

Ischemic colitis incidence following abdominal aortic reconstruction: a prospective study.

作者信息

Ernst C B, Hagihara P F, Daughtery M E, Sachatello C R, Griffen W O

出版信息

Surgery. 1976 Oct;80(4):417-21.

PMID:968729
Abstract

With few exceptions, the incidence of left colon ischemia following abdominal aortic reconstruction has been reported to be one to 2 percent. All reports of such ischemic events are retrospective analyses of clinically manifest or autopsy. Fifty patients were studied prospectively to determine more accurately the incidence of this complication. Aortic reconstruction was performed in 23 patients for occlusive disease (OD) and in 27 for aneurysm disease (AD). No emergency operations were performed. All patients underwent colonoscopy within 4 days of operation. Three instances of colon ischemia were noted, an incidence of 6 percent (OD 4.3 percent, AD 7.4 percent). Each patient recovered uneventfully. Two patients had diarrhea, but only after colon ischemia was recognized. Arteriographic opacification of the inferior mesenteric artery by the superior mesenteric artery collateral (meandering mesenteric artery) was documented in 35 percent of patients with OD and in 27 percent of patients with AD. Colon ischemia did not develop when this collateral was identified. The inferior mesenteric artery was patent at the aorta in all who developed colon ischema. Although clinically significant colitis following aortic reconstruction is rare, colonoscopy after operation may prove to be valuable for early recognition of ischemic changes before clinical manifestations preclude effective management.

摘要

除少数例外情况外,据报道腹主动脉重建术后左半结肠缺血的发生率为1%至2%。所有关于此类缺血事件的报告均为对临床表现或尸检的回顾性分析。对50例患者进行了前瞻性研究,以更准确地确定这种并发症的发生率。23例患者因闭塞性疾病(OD)接受了主动脉重建,27例因动脉瘤疾病(AD)接受了主动脉重建。未进行急诊手术。所有患者在术后4天内接受了结肠镜检查。发现3例结肠缺血,发生率为6%(OD为4.3%,AD为7.4%)。每位患者均顺利康复。2例患者出现腹泻,但均在结肠缺血被发现之后。在35%的OD患者和27%的AD患者中记录到肠系膜上动脉侧支(迂曲肠系膜动脉)使肠系膜下动脉造影显影。当发现这种侧支时,未发生结肠缺血。所有发生结肠缺血的患者肠系膜下动脉在主动脉处均通畅。虽然主动脉重建术后具有临床意义的结肠炎很少见,但术后结肠镜检查可能对在临床表现妨碍有效治疗之前早期识别缺血性改变具有重要价值。

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