Ernst C B, Hagihara P F, Daugherty M E, Griffen W O
Ann Surg. 1978 Jun;187(6):641-6. doi: 10.1097/00000658-197806000-00009.
Fifty-two patients undergoing nonemergent abdominal aortic aneurysmectomy were prospectively studied to determine when the inferior mesenteric artery (IMA) could be ligated without subsequent development of ischemic colitis. Cannulation of the severed distal IMA for blood pressure measurement (IMA stump pressure) before and after aortic reconstruction was attempted in all and possible in 39 individuals. In 13 the IMA was thrombosed precluding pressure measurement. Prereconstruction and postreconstruction mean IMA stump and systemic arterial blood pressure measurements were computed and mean IMA/systemic pressure ratios were calculated. All patients underwent postoperative colonoscopy. One patient developed postoperative ischemic colitis. Her postreconstruction ratio was 0.37 and her postreconstruction mean IMA blood pressure was 33 mmHg, the only individual with a ratio and pressure less than 0.40 and 40 mmHg, respectively. Internal iliac arterial pulsations could not be restored in two patients. Although postresection indices were less than preresection indices in both, postresection indices were greater than 0.40 and 40 mmHg. In this study, if the IMA was thrombosed or if postresection pressures and ratios measured greater than 40 mmHg and 0.40 respectively, ischemic colitis did not develop following abdominal aortic aneurysmectomy. This simple test may prove useful in identifying patients at risk for developing postoperative ischemic colitis or if IMA revascularization is required.
对52例行非急诊腹主动脉瘤切除术的患者进行了前瞻性研究,以确定何时可以结扎肠系膜下动脉(IMA)而不继发缺血性结肠炎。在所有患者中均尝试在主动脉重建前后对离断的IMA远端进行插管以测量血压(IMA残端压力),39例患者成功进行了测量。13例患者的IMA已形成血栓,无法进行压力测量。计算重建前和重建后IMA残端和全身动脉血压的平均值,并计算平均IMA/全身压力比值。所有患者均接受术后结肠镜检查。1例患者发生术后缺血性结肠炎。她重建后的比值为0.37,重建后IMA平均血压为33 mmHg,是唯一比值和压力分别低于0.40和40 mmHg的患者。2例患者的髂内动脉搏动未能恢复。虽然二者切除后的指标均低于切除前的指标,但切除后的指标均大于0.40和40 mmHg。在本研究中,如果IMA已形成血栓,或切除后测量的压力和比值分别大于40 mmHg和0.40,则腹主动脉瘤切除术后不会发生缺血性结肠炎。这项简单的检查可能有助于识别有术后发生缺血性结肠炎风险的患者,或确定是否需要进行IMA血管重建。