线粒体对细胞钙离子信号的调控
Mitochondrial oversight of cellular Ca2+ signaling.
作者信息
Babcock D F, Hille B
机构信息
Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle 98195-7290, USA.
出版信息
Curr Opin Neurobiol. 1998 Jun;8(3):398-404. doi: 10.1016/s0959-4388(98)80067-6.
PMID:9687353
Abstract
Mitochondria, the metabolic powerhouses of the cell, can sequester and release large amounts of Ca2+. This import and export of Ca2+ helps to adjust energy production to cellular needs. Recent advances show that mitochondrial Ca2+ fluxes play a major role in normal Ca2+ signaling.
摘要
线粒体作为细胞的代谢动力源，能够摄取和释放大量钙离子。钙离子的这种进出有助于根据细胞需求调节能量产生。最新研究进展表明，线粒体钙离子通量在正常钙离子信号传导中起主要作用。
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