血液循环和氧合过程中的细胞聚集与破坏。
Cellular aggregation and destruction during blood circulation and oxygenation.
作者信息
Wright G, Sanderson J M
出版信息
Thorax. 1976 Aug;31(4):405-9. doi: 10.1136/thx.31.4.405.
Abstract
Platelet and leucocyte aggregation and severe haemolysis may occur in blood during the preparation of an extracorporeal circuit for open-heart surgery. Experiments with dog blood showed that both processes result from bubble oxygenation but not from circulation of diluted blood and that they appear to be inhibited by the presence of acid citrate dextrose and heparin, or citrate phosphate dextrose and heparin, but not by heparin alone.
摘要
在心脏直视手术体外循环准备过程中，血液中可能会发生血小板和白细胞聚集以及严重溶血。对狗血进行的实验表明，这两个过程均由气泡氧合导致，而非稀释血液的循环所致，并且它们似乎会受到酸性枸橼酸盐葡萄糖和肝素，或枸橼酸盐磷酸盐葡萄糖和肝素的抑制，但单独使用肝素则无此效果。
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