哮喘和阿司匹林特异反应患者的补体成分及免疫球蛋白E
Complement components and IgE in patients with asthma and aspirin idiosyncrasy.
作者信息
Delaney J C, Kay A B
出版信息
Thorax. 1976 Aug;31(4):425-7. doi: 10.1136/thx.31.4.425.
Abstract
Levels of circulating IgE, total haemolytic complement, and components C4 and C3 were measured in 16 asthmatics with aspirin idiosyncrasy and in control subjects. IgE levels were mostly within normal limits. No differences were found between the complement profiles-in particular the C4 levels-in the two groups. As low levels of C4 have been found in patients with intrinsic asthma, these results would suggest a fundamental difference between asthmatics with aspirin idiosyncrasy and others with intrinsic asthma.
摘要
对16名患有阿司匹林特异反应的哮喘患者和对照受试者测定了循环免疫球蛋白E（IgE）、总溶血补体以及补体C4和C3成分的水平。IgE水平大多在正常范围内。两组之间的补体谱，特别是C4水平，未发现差异。由于在特发性哮喘患者中发现了低水平的C4，这些结果表明患有阿司匹林特异反应的哮喘患者与其他特发性哮喘患者之间存在根本差异。
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