Myles-Worsley M, Coon H, Byerley W
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City 84132, USA.
Schizophr Res. 1998 May 25;31(2-3):131-9. doi: 10.1016/s0920-9964(98)00012-7.
The Spontaneous Selective Attention Task (SSAT) is a visual word-identification task that measures the type of selective attention that occurs spontaneously when there are multiple stimuli, all potentially relevant, and insufficient time to process each of them fully. The present study was designed to examine the sensitivity of the SSAT by comparing the performance of 40 schizophrenic inpatients and 30 schizophrenic outpatients to that of 70 normal controls. The pattern of results reported previously for schizophrenic inpatients versus normals was replicated, and these findings were extended to include schizophrenic outpatients in partial symptom remission. Schizophrenic inpatients and outpatients were just as accurate in identifying words as normals, but spontaneous selective attention under conditions of predictability was abnormal in both patient groups. Furthermore, the ability of the SSAT to discriminate between schizophrenic patients and controls was confirmed. A ratio measure of spontaneous selective attention had a sensitivity of 77% and a base rate of 9% in a normal population (when a cutoff value was set to minimize false positives and false negatives). Thus, the SSAT is a sensitive measure of an attentional phenotype that may be useful in genetic studies of schizophrenia.
自发选择性注意任务(SSAT)是一种视觉单词识别任务,用于测量在存在多个潜在相关刺激且没有足够时间对每个刺激进行充分处理时自发产生的选择性注意类型。本研究旨在通过比较40名精神分裂症住院患者、30名精神分裂症门诊患者与70名正常对照者的表现,来检验SSAT的敏感性。先前报道的精神分裂症住院患者与正常人的结果模式得到了重复,并且这些发现被扩展到包括部分症状缓解的精神分裂症门诊患者。精神分裂症住院患者和门诊患者在识别单词方面与正常人一样准确,但在可预测性条件下的自发选择性注意在两组患者中均异常。此外,证实了SSAT区分精神分裂症患者和对照者的能力。在正常人群中(当设定一个截止值以尽量减少假阳性和假阴性时),自发选择性注意的比率测量法的敏感性为77%,基础率为9%。因此,SSAT是一种对注意表型敏感的测量方法,可能在精神分裂症的遗传学研究中有用。