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[儿童泌尿系统感染的治疗。药物经济学方面]

[Treatment of urinary infections in children. Pharmaco-economic aspects].

作者信息

Chantraine J M

机构信息

Département Universitaire de Pédiatrie, Centre Hospitalier Régional de la Citadelle, Liège.

出版信息

Rev Med Liege. 1998 May;53(5):294-7.

PMID:9689886
Abstract

The risk factors for urinary tract infections in children are the young age, the severe febrile symptoms, any obstruction or dilatation of the urinary tract, recurrent episodes of acute disease and delay in initiating effective treatment. Today a new risk factor lies in the increasing resistance of germs to usually used antibiotics. The treatment therefore must be adapted to the local patterns of bacterial sensitives. To lower cost of the therapy, different ways may be followed: 1. To try to reduce the time of the inpatient management by using day-care or outpatient management possibilities. 2. To try to switch from the initial, heavy parenteral drugs to antibiotics to which the germ is sensitive and even to an adapted oral medication, when the child is doing well, is well hydrated and can tolerate the treatment. The outpatient management requires more compliance from the child and may be a burden for the parents.

摘要

儿童尿路感染的危险因素包括年龄小、高热症状严重、尿路任何梗阻或扩张、急性疾病反复发作以及开始有效治疗延迟。如今,一个新的危险因素在于病菌对常用抗生素的耐药性不断增加。因此,治疗必须适应当地的细菌敏感性模式。为降低治疗成本,可以采取不同的方法:1. 尝试通过日间护理或门诊管理的方式减少住院治疗时间。2. 当患儿情况良好、水分充足且能耐受治疗时,尝试从最初使用的强效静脉注射药物改用病菌敏感的抗生素,甚至改用合适的口服药物。门诊管理要求患儿有更高的依从性,对家长来说可能是一种负担。

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