Synthesis and biological activity studies of 3-arylaminomethyl-7H-6-(6 substituted-3-coumarino)-S-triazolo-[3,4-b][1,3,4]thiadiazines.

Several new 3-arylaminomethyl-7H-6-(6-substituted-3-coumarino)-s-triazol o-[3,4-b] [1,3,4]thiadiazines were synthesized by condensing 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles with 3-bromoacetyl-6-substituted coumarins in dioxan medium. The structures of newly synthesized compounds were established on the basis of analytical, NMR and mass spectral data. Some selected compounds from this series were subjected to antibacterial studies.