• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一些源自3-芳氨基甲基-4-氨基-5-巯基-1,2,4-三唑的N-桥连杂环化合物的合成、光谱研究及生物活性

Synthesis, spectral studies and biological activities of some N-bridged heterocycles derived from 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles.

作者信息

Holla B S, Udupa K V

机构信息

Department of P. G. Studies & Research in Chemistry Mangalore University, Mangalagangotri, India.

出版信息

Farmaco. 1992 Mar;47(3):305-18.

PMID:1503594
Abstract

Synthesis of four 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles starting from substituted anilines is described. These triazoles were employed in the synthesis of some N-bridged heterocycles carrying arylaminomethyl substituents. All the newly synthesized compounds were characterized by analytical, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial and antiviral properties.

摘要

描述了从取代苯胺出发合成四种3-芳基氨基甲基-4-氨基-5-巯基-1,2,4-三唑的方法。这些三唑被用于合成一些带有芳基氨基甲基取代基的N-桥连杂环。所有新合成的化合物均通过分析、核磁共振和质谱研究进行了表征。对一些新合成的化合物进行了抗菌和抗病毒性能筛选。

相似文献

1
Synthesis, spectral studies and biological activities of some N-bridged heterocycles derived from 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles.一些源自3-芳氨基甲基-4-氨基-5-巯基-1,2,4-三唑的N-桥连杂环化合物的合成、光谱研究及生物活性
Farmaco. 1992 Mar;47(3):305-18.
2
Synthesis, characterisation and antifungal activity of some N-bridged heterocycles derived from 3-(3-bromo-4-methoxyphenyl)-4-amino-5-mercapto-1,2,4-triazole.源自3-(3-溴-4-甲氧基苯基)-4-氨基-5-巯基-1,2,4-三唑的一些N-桥连杂环的合成、表征及抗真菌活性
Farmaco. 1996 Dec;51(12):793-9.
3
Synthesis and biological activity studies of 3-arylaminomethyl-7H-6-(6 substituted-3-coumarino)-S-triazolo-[3,4-b][1,3,4]thiadiazines.3-芳基氨基甲基-7H-6-(6-取代-3-香豆素基)-S-三唑并-[3,4-b][1,3,4]噻二嗪的合成及生物活性研究
Boll Chim Farm. 1998 May;137(5):169-72.
4
Studies on arylfuran derivatives- Part VIII. Synthesis, characterization and antibacterial activities of some 1-aminomethyl-3-substituted-4-[5-(4-nitrophenyl-2-furfurylidene)] amino-1,2,4-triazole-5-thiones.芳基呋喃衍生物的研究 - 第八部分。某些1-氨甲基-3-取代-4-[5-(4-硝基苯基-2-糠叉基)]氨基-1,2,4-三唑-5-硫酮的合成、表征及抗菌活性
Boll Chim Farm. 1998 Jul-Aug;137(7):233-8.
5
Synthesis and anti-microbial evaluation of some novel 1,2,4-triazole derivatives.一些新型1,2,4-三唑衍生物的合成与抗菌活性评估
Acta Pol Pharm. 2011 Mar-Apr;68(2):213-21.
6
Studies on the synthesis and biological activity of 3-(substituted anilinomethyl)-4-(5-substituted-2-furfurylidene)amino-1,2,4 -triazole-5- thiones and their Mannich bases.3-(取代苯胺甲基)-4-(5-取代-2-糠叉基)氨基-1,2,4-三唑-5-硫酮及其曼尼希碱的合成与生物活性研究
Boll Chim Farm. 1996 Dec;135(11):638-42.
7
Regioselective reaction: synthesis, characterization and pharmacological studies of some new Mannich bases derived from 1,2,4-triazoles.区域选择性反应:一些源自1,2,4-三唑的新型曼尼希碱的合成、表征及药理学研究
Eur J Med Chem. 2009 Sep;44(9):3784-7. doi: 10.1016/j.ejmech.2009.04.038. Epub 2009 May 5.
8
Synthesis, characterization and antibacterial activities of some N-bridged heterocycles containing triazole, quinoline and nitrofuran moieties.一些含三唑、喹啉和硝基呋喃部分的N-桥连杂环化合物的合成、表征及抗菌活性
Boll Chim Farm. 2002 Mar-Apr;141(2):105-9.
9
Synthesis and biological action of 3,4-disubstituted 5-arylsulphonylamine-1,2,4-triazoles.
Pharmazie. 1999 Aug;54(8):588-9.
10
Synthesis of some 4-(alkylidene/arylidene)amino-2,4-dihydro-5- (2-thienyl)-3H-1,2,4-triazole-3-thiones tested for antimicrobial activity.对一些经抗菌活性测试的4-(亚烷基/亚芳基)氨基-2,4-二氢-5-(2-噻吩基)-3H-1,2,4-三唑-3-硫酮的合成。
Boll Chim Farm. 2001 Nov-Dec;140(6):417-21.

引用本文的文献

1
Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors.新型吡唑啉基吲哚衍生物的合成及抗癌活性:基于药效团相互作用和对接研究鉴定新型 EGFR 抑制剂。
Int J Mol Sci. 2022 Jun 11;23(12):6548. doi: 10.3390/ijms23126548.
2
2-Phenoxy-acetohydrazide.2-苯氧基乙酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 4;66(Pt 1):o53-4. doi: 10.1107/S1600536809051344.
3
2-(2-Chloro-phen-oxy)acetohydrazide.2-(2-氯苯氧基)乙酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 4;66(Pt 1):o31-2. doi: 10.1107/S1600536809051356.
4
2-(4-Methyl-anilino)acetohydrazide.2-(4-甲基苯胺基)乙酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 26;65(Pt 9):o2234. doi: 10.1107/S1600536809033169.
5
4-Amino-3-[(4-methoxy-phen-yl)amino-meth-yl]-1H-1,2,4-triazole-5(4H)-thione.4-氨基-3-[(4-甲氧基-苯基)氨基甲基]-1H-1,2,4-三唑-5(4H)-硫酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 22;65(Pt 9):o2213. doi: 10.1107/S1600536809032607.
6
2-(4-Methyl-phen-oxy)acetohydrazide.2-(4-甲基苯氧基)乙酰肼
Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 18;67(Pt 1):o165. doi: 10.1107/S1600536810051937.