• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名播散性隐球菌病患儿的特发性CD4+淋巴细胞减少症

Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis.

作者信息

Menon B S, Shuaib I L, Zamari M, Haq J A, Aiyar S, Noh L M

机构信息

Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.

出版信息

Ann Trop Paediatr. 1998 Mar;18(1):45-8. doi: 10.1080/02724936.1998.11747925.

DOI:10.1080/02724936.1998.11747925
PMID:9692001
Abstract

We describe a Malay girl with disseminated cryptococcosis affecting the lungs, liver, lymph nodes and bones. The diagnosis was made by culture of the bone marrow. Tests of immune function showed that she was HIV-negative but the CD4 percentage was persistently low. Idiopathic CD4+ T-lymphocytopenia was diagnosed. The child died despite two courses of anti-fungal therapy.

摘要

我们描述了一名患有播散性隐球菌病的马来女孩,该病累及肺部、肝脏、淋巴结和骨骼。诊断通过骨髓培养做出。免疫功能测试显示她HIV阴性,但CD4百分比持续偏低。诊断为特发性CD4 + T淋巴细胞减少症。尽管接受了两个疗程的抗真菌治疗,该患儿仍死亡。

相似文献

1
Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis.一名播散性隐球菌病患儿的特发性CD4+淋巴细胞减少症
Ann Trop Paediatr. 1998 Mar;18(1):45-8. doi: 10.1080/02724936.1998.11747925.
2
Disseminated cryptococcosis with granuloma formation in idiopathic CD4 lymphocytopenia.特发性 CD4 淋巴细胞减少症患者的播散性隐球菌病伴肉芽肿形成。
J Infect Chemother. 2020 Feb;26(2):257-260. doi: 10.1016/j.jiac.2019.07.006. Epub 2019 Jul 23.
3
Disseminated cryptococcosis in an HIV-seronegative pregnant woman with transient T-lymphocytopenia: a case report and review of the literature.一名HIV血清学阴性且伴有短暂性T淋巴细胞减少症的孕妇发生播散性隐球菌病:病例报告及文献复习
Southeast Asian J Trop Med Public Health. 2014 May;45(3):647-53.
4
Pleural cryptococcosis with idiopathic CD4 positive T-lymphocytopenia.伴有特发性CD4阳性T淋巴细胞减少症的胸膜隐球菌病
Intern Med. 2004 Oct;43(10):977-81. doi: 10.2169/internalmedicine.43.977.
5
Disseminated cryptococcosis in a case of idiopathic CD 4 + lymphocytopenia.一例特发性CD4 +淋巴细胞减少症患者的播散性隐球菌病
J Assoc Physicians India. 2007 Jul;55:527-8.
6
[CNS cryptococcosis with idiopathic CD4+ T lymphocytopenia].[中枢神经系统隐球菌病合并特发性CD4+ T淋巴细胞减少症]
Rinsho Shinkeigaku. 2000 Mar;40(3):249-53.
7
Invasive fungal infection by Cryptococcus neoformans var. grubii with bone marrow and meningeal involvement in a HIV-infected patient: a case report.新型隐球菌变种格卢氏菌骨髓和脑膜侵犯合并 HIV 感染患者的侵袭性真菌感染:一例报告。
BMC Infect Dis. 2019 Mar 4;19(1):220. doi: 10.1186/s12879-019-3831-8.
8
Cryptococcosis and idiopathic CD4 lymphocytopenia.隐球菌病与特发性CD4淋巴细胞减少症。
Medicine (Baltimore). 2007 Mar;86(2):78-92. doi: 10.1097/md.0b013e31803b52f5.
9
[Questions and answers regarding the article "Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis"].[关于“一名播散性隐球菌病患儿的特发性CD4 + T淋巴细胞减少症”一文的问答]
Zhonghua Er Ke Za Zhi. 2006 Jun;44(6):475-6.
10
Cryptococcosis and deficiency of interleukin12r.隐球菌病与白细胞介素12受体缺乏
Pediatr Infect Dis J. 2008 Jul;27(7):673. doi: 10.1097/INF.0b013e318179263a.

引用本文的文献

1
Update on disseminated cryptococcosis in non-HIV infected children.非HIV感染儿童播散性隐球菌病的最新情况
Ital J Pediatr. 2025 Jun 7;51(1):177. doi: 10.1186/s13052-025-02011-w.
2
Pulmonary Cryptococcus infections as a manifestation of idiopathic CD4 lymphocytopenia: case report and literature review.肺隐球菌感染作为特发性 CD4 淋巴细胞减少症的一种表现:病例报告及文献复习。
BMC Infect Dis. 2019 Oct 17;19(1):862. doi: 10.1186/s12879-019-4453-x.
3
Humanized mouse models reveal an immunologic classification of idiopathic CD4 lymphocytopenia subtypes.
人源化小鼠模型揭示特发性 CD4 淋巴细胞减少症亚型的免疫分类。
JCI Insight. 2019 Jul 25;4(14). doi: 10.1172/jci.insight.127802.
4
Malaysia's First Transplanted Case of Chronic Granulomatous Disease: The Journey of Overcoming Obstacles.马来西亚首例慢性肉芽肿病移植病例:克服重重困难的历程
Children (Basel). 2016 May 17;3(2):9. doi: 10.3390/children3020009.
5
Idiopathic CD4 Lymphocytopenia: Spectrum of opportunistic infections, malignancies, and autoimmune diseases.特发性CD4淋巴细胞减少症:机会性感染、恶性肿瘤和自身免疫性疾病谱
Avicenna J Med. 2013 Apr;3(2):37-47. doi: 10.4103/2231-0770.114121.
6
A case of pulmonary cryptococcosis with non-small cell lung cancer in idiopathic CD4+ T-lymphocytopenia.一例特发性CD4 + T淋巴细胞减少症合并非小细胞肺癌的肺隐球菌病病例。
Yonsei Med J. 2005 Feb 28;46(1):173-6. doi: 10.3349/ymj.2005.46.1.173.
7
Idiopathic CD4+ T-lymphocytopenia in a boy with Down syndrome. Report of a patient and a review of the literature.
Eur J Pediatr. 2004 Feb;163(2):122-3. doi: 10.1007/s00431-003-1375-8. Epub 2003 Dec 19.
8
A cryptic cause of cryptococcal meningitis.隐球菌性脑膜炎的一个隐秘病因。
CMAJ. 2003 Feb 18;168(4):451-2.