Gürgey A, Gurler A, Oner A F, Mesci L, Kirazli S
Department of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Clin Rheumatol. 1998;17(3):186-8. doi: 10.1007/BF01451044.
The plasma levels of thrombomodulin (TM) in 34 patients with Behçet's disease and 79 healthy control subjects were studied. Eight patients had the factor V Leiden (FVL) mutation. The TM level was significantly lower in patients with the FVL mutation than in patients without the mutation and in the healthy controls (p < 0.05 and p < 0.01). However, there was no difference in overall mean plasma TM concentration between the patients without the mutation and the healthy controls.
研究了34例白塞病患者和79例健康对照者的血浆血栓调节蛋白（TM）水平。8例患者存在因子V莱顿（FVL）突变。有FVL突变的患者的TM水平显著低于无突变的患者和健康对照者（p<0.05和p<0.01）。然而，无突变的患者与健康对照者之间的总体平均血浆TM浓度没有差异。
