Akpolat I, Ozyilkan E, Karagöz F, Akpolat T, Kandemir B
Department of Pathology, Ondokuz Mayis University School of Medicine, Samsun, Turkey.
Int Urol Nephrol. 1998;30(3):349-55. doi: 10.1007/BF02550322.
Hepatitis C virus (HCV) is the major cause of posttransfusion non-A, non-B hepatitis. Haemodialysis patients carry the risk of HCV infection. The aim of this study is to compare the morphological changes related to chronic HCV infection found in haemodialysis and nonuraemic patients. Liver biopsies from nine haemodialysis patients and 37 patients with normal renal function were studied. This study shows that haemodialysis patients may have less active and progressive chronic hepatitis C than patients with normal renal function. The number of patients in this study is limited, therefore further studies are needed for definite conclusion.
丙型肝炎病毒(HCV)是输血后非甲非乙型肝炎的主要病因。血液透析患者存在感染HCV的风险。本研究的目的是比较血液透析患者和非尿毒症患者中与慢性HCV感染相关的形态学变化。对9例血液透析患者和37例肾功能正常患者的肝活检进行了研究。本研究表明,与肾功能正常的患者相比,血液透析患者的慢性丙型肝炎可能不那么活跃且进展较慢。本研究中的患者数量有限,因此需要进一步研究以得出明确结论。