Evans D F
St Bartholomew's, London, UK.
Eur J Cancer Prev. 1998 May;7 Suppl 2:S79-80. doi: 10.1097/00008469-199805000-00013.
Epidemiological evidence suggests that 80-90% of colorectal cancer is caused by dietary and environmental factors and that the prevalence of cancer can be altered in low-risk patients by long-term alterations in dietary fibre ingestion. It has therefore become increasingly important to examine the available data on colonic pH and transit, and on faecal short-chain fatty acids in different groups, in order to establish the relationship between fibre intake, colonic acidification and the predisposition to cancer in different ethnic groups.
流行病学证据表明，80%-90%的结直肠癌由饮食和环境因素引起，并且通过长期改变膳食纤维摄入量，低风险患者的癌症患病率可以改变。因此，审查不同人群中有关结肠pH值、转运以及粪便短链脂肪酸的现有数据，以确定不同种族群体中纤维摄入量、结肠酸化与癌症易感性之间的关系变得越来越重要。
