Colliander E B, Strigård K, Westblad P, Rolf C, Nordenström J
Department of Orthopaedics, Huddinge University Hospital, Karolinska Institute, Sweden.
Eur J Surg. 1998 Jul;164(7):489-94. doi: 10.1080/110241598750005822.
To evaluate the effect of surgery on muscular strength and endurance in patients with primary hyperparathyroidism (HPT).
Prospective open study.
University hospital, Sweden.
Nine patients undergoing HPT surgery and nine matched patients undergoing thyroid resection who acted as controls.
Concentric and eccentric endurance was evaluated with a test comprising 100 repeatedly executed muscle action at 90 degrees.s-1. Blood samples obtained before and after operation were analysed for calcium, phosphate, thyroid stimulating hormone (TSH), and parathyroid hormone (PTH) concentrations.
Peak torque during maximum voluntary concentric and eccentric muscle actions at 90 degrees.s-1 before, three months and one year after operation.
There were no differences in concentric and eccentric peak torque before and after operation either within or between groups. Concentric and eccentric endurance were similar in the HPT group and controls before as well as after operation. The return of calcium and PTH concentrations to their reference ranges after parathyroidectomy did not correlate with changes in concentric and eccentric peak torque.
The subjective improvement in muscle endurance which is often encountered in patients with HPT after operation is not associated with an objective increase in muscle strength or endurance as measured by isokinetic muscle performance.
评估手术对原发性甲状旁腺功能亢进症（HPT）患者肌肉力量和耐力的影响。
前瞻性开放性研究。
瑞典大学医院。
9例行HPT手术的患者和9例匹配的行甲状腺切除术的患者作为对照。
通过一项包括在90度·秒⁻¹下重复执行100次肌肉动作的测试来评估向心和离心耐力。分析手术前后采集的血样中的钙、磷、促甲状腺激素（TSH）和甲状旁腺激素（PTH）浓度。
术前、术后3个月和1年时，在90度·秒⁻¹的最大自主向心和离心肌肉动作过程中的峰值扭矩。
组内和组间手术前后的向心和离心峰值扭矩均无差异。HPT组和对照组术前及术后的向心和离心耐力相似。甲状旁腺切除术后钙和PTH浓度恢复到参考范围与向心和离心峰值扭矩的变化无关。
HPT患者术后常出现的肌肉耐力主观改善与等速肌肉性能测量的肌肉力量或耐力客观增加无关。
