Hedman I, Grimby G, Tisell L E
Acta Chir Scand. 1984;150(7):521-4.
Severe muscular weakness and increased fatigability are occasionally encountered in patients with hyperparathyroidism (HPT). An unselected series of 15 HPT patients was studied to assess if subjective fitness could be associated with detectable muscular dysfunction at objective measurements comparing muscle strength before and after surgery. Significant increase in isokinetic strength of knee extension and knee flexion at higher angular velocities was found three months after surgery, suggesting effect predominantly on type II (fast twitch) muscle fibres. The results of the study support the clinical impression that HPT surgery may be beneficial to patients with muscular symptoms.
甲状旁腺功能亢进症（HPT）患者偶尔会出现严重的肌肉无力和疲劳感增加的症状。我们对一组未经挑选的15例HPT患者进行了研究，旨在通过比较手术前后的肌肉力量客观测量结果，评估主观健康状况是否与可检测到的肌肉功能障碍相关。术后三个月，发现较高角速度下膝关节伸展和屈曲的等速肌力显著增加，这表明主要对II型（快肌纤维）肌肉纤维产生了影响。该研究结果支持了临床印象，即HPT手术可能对有肌肉症状的患者有益。
