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[克罗恩病的疑难诊断]

[Difficult diagnosis of Crohn's disease].

作者信息

Brandes J W, Eulenburg F

出版信息

Z Gastroenterol. 1976 May;14(3):400-6.

PMID:969783
Abstract

It is often difficult to diagnose Crohn's disease because of the numerous clinical symptoms. In a retrospective study from 1963-1975 the initial diagnosis was examined in 101 patients with Crohn's disease. In 22% of the patients the initial diagnosis was correct, in 78% one or more wrong diagnoses were made. The most regular wrong diagnosis was colitis ulcerosa (30%). 41 patients were unnecessarily treated surgically before the correct diagnosis was established. The mean time from the on-set of the symptoms until the correct diagnosis was 3.6 years, the mean time from the first wrong diagnosis to the correct diagnosis, 2.9 years. In the later few years a decrease in wrong diagnoses, an increase in initially correct diagnoses and a shortening of the interval between beginning of symptoms until final diagnosis are recognizable. The possible reasons are discussed.

摘要

由于克罗恩病的临床症状多种多样,其诊断往往很困难。在一项1963年至1975年的回顾性研究中,对101例克罗恩病患者的初始诊断进行了检查。22%的患者初始诊断正确,78%的患者有一个或多个错误诊断。最常见的错误诊断是溃疡性结肠炎(30%)。41例患者在确诊前接受了不必要的手术治疗。从症状出现到正确诊断的平均时间为3.6年,从首次错误诊断到正确诊断的平均时间为2.9年。在随后的几年里,可以看出错误诊断有所减少,初始正确诊断有所增加,从症状开始到最终诊断的间隔时间缩短。文中讨论了可能的原因。

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